| 一种新的趋化因子I-TAC |
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| 引用本文： | 祝先进,苏东辉. 一种新的趋化因子I-TAC[J]. 国际免疫学杂志, 2006, 29(5): 330-334 |
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| 作者姓名： | 祝先进 苏东辉 |
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| 作者单位： | 350004,福州,福建医科大学免疫学系;福建医科大学免疫学系 |
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| 基金项目： | 教育部重点项目（03064） |
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| 摘 要： | 趋化因子是一系列具有募集细胞迁移功能的细胞因子。干扰素诱导的T细胞α亚族趋化剂(I-TAC)是近年新发现的一种趋化因子,属于CXC家族。已经发现I-TAC不仅具有指导细胞迁移的趋化因子的基本功能,而且还参与调控血管生成及细胞增殖的过程。研究I-TAC结构、生物学功能以及与疾病的关系具有重要的意义。
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| 关 键 词： | 趋化因子 I-TAC CXCR3 移植 |
| 文章编号： | 1673-4394(2006)05-0330-04 |
| 收稿时间： | 2005-10-25 |
| 修稿时间： | 2005-10-25 |
I-TAC:A Novel Chemokine |
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| ZHU Xian-jin. I-TAC:A Novel Chemokine[J]. International Journal of Immunology, 2006, 29(5): 330-334 |
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| Authors: | ZHU Xian-jin |
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| Affiliation: | Department of Immuology, Fufian Medical University, Fuzhou 350004 |
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| Abstract: | IFN-inducible T cell alpha chemoattractant (I-TAC/CXCL11) is a recently discovered member of the CXC chemokine family. It has been found that I-TAC not only plays a general role in leukocyte recruitment, but also takes part in the modulation of angiogenesis and cell proliferation. It is important to further investigate the structure and biological functions of I-TAC and its association with diseases. |
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| Keywords: | Chemokine I-TAC CXCR3 Transplantation |
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