非淋菌性尿道炎病原体检测及药物敏感分析

目的探讨非淋菌性尿道炎病原体感染及支原体药物敏感和耐药情况。方法采集500例男性尿道、女性宫颈分泌物标本,进行衣原体、支原体培养鉴定和药物敏感试验。结果支原体培养总阳性率55.8%(279/500),其中解脲脲原体(UU)、人型支原体(Mh)及UU+Mh混合感染的阳性率分别为23.6%(118/500),4.4%(22/500)和27.8%(139/500)。药敏试验结果显示:对支原体敏感前三位的药物分别是交沙霉素、强力霉素、美满霉素,支原体耐药性前三位的药物分别是左氧氟沙星、红霉素、克林霉素。结论性病门诊患者中支原体感染率较衣原体高,以UU为主;首选药物为交沙霉素;支原体耐药性最高的药物是左氧氟沙星;支原体培养和药敏试验对指导本医院临床合理用药具有重要意义。

The Analysis on Pathogen and Medicine Sensitivity of the Nongococcal Urethritis

Objective To investigate the Pathogen of the Nongococcal Urethritis and the drug resistance of the themycoplasma.Methods The urethra secretions collected from 350 male patients bearded the Nongococcal Urethritis in 4 years in our hospital and the servical secretions from 350 female patients, were given Chlamydia culture, mycoplasma culture and drug sensitive test.Results The total positive rate of mycoplasma was 55.8%(279/500) from the nereal department and theurology department in our hospital, the Ureaplasma urealyticum was 23.6%(118/500), the Mycoplasma hominis was 4.4%(22/500), the mixed infection rate was 27.8%(139/500). The drug sensitive test result: the first sensitive drugs to mycoplasma was the Josamycine, the second was the Doxycycline, the third was the Mincycline. The resistant drug first was the Levofloxacin, second was the erythrocin, third was the clindamycin.Conclusion The infection rate of the mycoplasma was higher than the Chlamydia from patients bearded the Nongococcal Urethritis in the nereal department and the urology department in our hospital. The Ureaplasma urealyticum was in the first place, the sensitive drug first was the Josamycine, the resistant drug first was the Levofloxacin. The Chlamydia culture and the drug sensitivity test were important for rational drug use.