高原移居汉族凝血纤溶系统的研究

目的　研究高原环境下移居汉族血液凝血纤溶系统的状态。方法　检测 4 8例移居汉族血浆组织型纤溶酶原激活物(t-PA)、纤溶酶原激活物抑制剂 (PAI)和纤维蛋白原 (Fbg)含量 ,并与内地健康人进行比较。 结果　与内地健康人比较 ,移居者组t-PA活性降低 (P <0 .0 5 ) ,PAI活性升高 (P <0 .0 5 ) ,Fbg含量升高 (P <0 .0 5 )。 结论　高原环境下移居汉族血液处于高凝状态

Study on Blood Coagulation and Fibrinolysis System of Han Nationality That Migrated to Plateau

Objective To study the state of blood coagulation and fibrinolysis system of Han natinality that migrated to plateau.Methods The activites of plasmiongen activator of tissue type (t-PA),Plasmiongen activator inhibitor(PAI) and the level of fibrinogen (Fbg) in the plasma, were measured, and then compared with that of healthy controls who 1ived in inland. Results The activity of t-PA decreased, and the activity of PAI and the level of Fbg increased, when compared with that of the healthy controls who came from inland ( P <0.05).Conclusion It is suggested that the blood of Han nationality that migrate to plateau be in a high coagulation state.