云南引种玛咖对小鼠非特异性免疫、抗疲劳、耐缺氧功能的影响

目的:观察云南栽培的紫、白、黄3种色型玛咖对小鼠非特异性免疫、抗疲劳、耐缺氧功能的影响,评价3种色型玛咖的保健功效,为其保健食品开发及活性物质基础的进一步研究提供实验依据。方法:采用环磷酰胺诱导免疫低下、负重游泳、常压缺氧模型,选用单核巨噬细胞的吞噬能力、负重游泳时间、缺氧耐受时间作为评价指标。结果:3种色型玛咖均能提高免疫低下小鼠的单核巨噬细胞吞噬能力(P<0.01);均能明显延长小鼠负重游泳时间(P<0.01或P<0.001),其中紫玛咖的延长率最高,黄玛咖次之,白玛咖最弱;紫、黄玛咖均能明显提高小鼠常压耐缺氧时间(P<0.001),紫玛咖的延长率最高,黄玛咖次之;结论:云南栽培的3种色型玛咖功效与相关文献报道的秘鲁玛咖相似,其中紫玛咖的作用最优,黄玛咖次之,白玛咖最弱。

The Effects of Introduction Lepidium Meyenii in Yunnan Province on Nonspecific Immunity,Fatigue and Hypoxia Function

Objective： To observe the effects of the cultivation of purple, white and yellow color types of Lepidium meyenii （Maca） cultivation in Yunnau on nonspedific immunity, fatigue resistance and hypoxia tolerance function, meanwhile, to provide the experimental basis for the development of health food and the further research of the active material. Methods ： The mouse models of cyclophosphamide induced immunosuppression, weight load- ing swimming and normobaric hypoxia were made. The mononuclear macrophage phagochtosis ability, weight load- ing swimming time and hypoxia tolerance time were chose as the evaluation index. Results： The mononuclear phag- ocytic capacity of immunity deficiency mice was improved by three kinds of Maca （P 〈 0. 01 ） ; Three color types of Maca could significant extend the weight loading swimming time of mice （ P 〈 0. 01 or P 〈 0. 001 ）, especially the purple Maca, then the yellow Maca. The hypoxia tolerance time were extended by the purple and yellow Maca （ P 〈 0. 001 ）, especially the purple Maca. Conclusion ： The three color types of Maca cultivated in Yunnan had the similar efficacy with which cultivated in Peru as reported, the efficacy of purple Maca was the most significant, then the yellow one, and then the white one.