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肥胖急性心衰患者BNP切点的临床探讨
引用本文:孙树印,屈峰,李慧. 肥胖急性心衰患者BNP切点的临床探讨[J]. 心血管康复医学杂志, 2011, 20(3): 208-211. DOI: 10.3969/j.issn.1008-0074.2011.03.05
作者姓名:孙树印  屈峰  李慧
作者单位:山东济宁市第一人民医院,山东,济宁,272111
摘    要:目的:探讨肥胖急性心衰患者的血浆脑钠肽(BNP)切点,为更科学地诊断、评估、治疗心衰以及判断预后提供依据。方法:对住院治疗的68例肥胖(体重指数〉23kg/m2)急性心衰患者,采用美国Cardio Dynamics公司生产的无创心排量(ICG)模块,利用生物阻抗法进行无创血流动力学监测,计算出心排量和其它血液动力学参数,采用Triage BNP检测仪进行床旁即时BNP检测。急性心衰判断根据临床症状和血流动力学检测结果确定,分析不同BNP切点的敏感性与特异性,建立受检者工作特征曲线(ROC)。结果:肥胖急性心衰患者的BNP切点在80.4pg/ml时,ROC曲线下面积0.922,敏感性94.02%、特异性72.17%、准确性83.11%、阴性预测值88.45%、阳性预测值79.51%,对心衰诊断效率最高。结论:肥胖急性心衰患者血浆BNP的切点取80.4pg/ml时,对心衰诊断效率最高,其切点的建立可提高对心衰诊断的准确率。

关 键 词:利钠肽,脑  肥胖  心力衰竭

Clinical study of incisor point of BNP in obese patients with acute heart failure
SUN Shu-yin,QU Feng,LI Hui. Clinical study of incisor point of BNP in obese patients with acute heart failure[J]. Chinese Journal of Cardiovascular Rehabilitation Medicine, 2011, 20(3): 208-211. DOI: 10.3969/j.issn.1008-0074.2011.03.05
Authors:SUN Shu-yin  QU Feng  LI Hui
Affiliation:Department of Emergency Medicine,First People′s Hospital of Jining City,Jining,Shandong,272111,China
Abstract:Objective: To explore incisor point of plasma brain natriuretic peptide(BNP) in obese patients with acute heart failure and provide evidence for more scientific evaluation,treatment and judgment of prognosis of heart failure.Methods: A total of 68 obese(body mass index,BMI>23 kg/m2) inpatients with acute heart failure were enrolled.Module of impedance cardiogram(ICG,Cardio Dynamics Company,U.S.) and bioelectrical impedance method were used to perform non-invasive hemodynamic monitoring,cardiac output and ot...
Keywords:Natriuretic peptide  brain  Obesity  Heart failure  
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