| 灵芝孢子胶囊的质量控制 |
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| 引用本文： | 曾平,尹东锋,付臻宁. 灵芝孢子胶囊的质量控制[J]. 中国药师, 2011, 14(6): 793-794 |
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| 作者姓名： | 曾平 尹东锋 付臻宁 |
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| 作者单位： | 1. 兰州军区乌鲁木齐总医院药剂科,乌鲁木齐,830000
2. 新疆石河子大学药学院 |
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| 基金项目： | 兰州军区医药卫生科研项目 |
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| 摘 要： | 目的:建立灵芝孢子胶囊质量控制方法。方法:采用显微镜鉴别破壁灵芝孢子。采用TLC法鉴别灵芝。利用硫酸-蒽酮显色,采用紫外分光光度法在波长625nm处测定制剂中多糖的含量。结果:显微镜下可明显观察到卵形孢子。TLC色谱可明显鉴别灵芝。灵芝多糖在5.25～31.50μg·ml-1的浓度范围内线性关系良好,r=0.999 8（n=6）;平均回收率99.07%,RSD=1.08%。结论:定性、定量方法简单、快捷、可靠、准确,可作为该制剂的质量控制。
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| 关 键 词： | 灵芝多糖 紫外分光光度法 含量测定 硫酸-蒽酮法 质量标准 |
Quality Control of Ganoderma Spore Capsules |
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| Zeng Ping,Yin Dongfeng,Fu Zhenning. Quality Control of Ganoderma Spore Capsules[J]. China Pharmacist, 2011, 14(6): 793-794 |
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| Authors: | Zeng Ping Yin Dongfeng Fu Zhenning |
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| Affiliation: | Zeng Ping~1,Yin Dongfeng~1,Fu Zhenning~2(1.Department of Pharmacy,Urumqi General Hospital,Lanzhou Military Region of PLA,Urumqi 830000,China,2.School of Pharmacy,Xinjiang Shihezi University) |
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| Abstract: | Objective： To explore the quality control method of ganoderma spore capsules. Method： Ganoderma spore was identified by a microscope. Ganoderma was identified by TLC. The coloration was used with sulphuric acid-anthrone, then ganoderma polysaccharide in ganoderma spore capsules was determined by UV spectrophotometry at 625 nm. Result： The ovoid spore could be observed by the microscope and ganoderma could be identified by TLC. A good linear range was shown over the concentration range of 5. 25- 31, 50 μg· ml^-1 （r = 0. 999 8 ）. The average recovery was 99.07% with RSD of 1.08%. Conclusion： The method is sample, rapid, reliable and accurate. It can be applied in the quality control of the preparation. |
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| Keywords: | Ganoderma polysaccharide UV spectrophotometry Sulphuric acid-anthrone Quality standard |
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