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基层医院尿激酶静脉溶栓治疗急性心肌梗死128例临床观察
引用本文:刘勇,刘艳丽,周永立,赵洪磊.基层医院尿激酶静脉溶栓治疗急性心肌梗死128例临床观察[J].岭南心血管病杂志,2011,17(3):218-220.
作者姓名:刘勇  刘艳丽  周永立  赵洪磊
作者单位:1. 东莞市桥头医院内科,广东东莞,523323
2. 东莞市人民医院心内科,广东东莞,523538
摘    要:目的探讨基层医院早期尿激酶静脉溶栓治疗急性心肌梗死的临床效果。方法回顾性分析128例以尿激酶静脉溶栓治疗的急性心肌梗死患者的临床资料,根据发病时间将患者分为3组(〈3h组,3~6h组及6~12h组),比较3组经溶栓治疗后的再通率。结果 128例急性心肌梗死患者接受溶栓治疗,总再通率71.09%,无死亡患者。〈3h组再通率显著高于3~6h组93.33%(28/30)vs.68.49%(50/73),P〈0.05]及6~12h组93.33%(28/30)vs.52.00%(13/25),P〈0.05],差异有统计学意义。溶栓后2h内出现心律失常30例(23.43%),溶栓24h出现上消化道出血2例(1.56%),低血压2例(1.56%),急性左心衰6例(4.68%),经对症治疗未造成严重后果。结论尿激酶早期溶栓治疗急性心肌梗死患者能有效地挽救濒死心肌,改善患者的预后,是一种有效治疗方法。

关 键 词:心肌梗死  尿激酶  溶栓  再通

Thrombolysis therapy by intravenous administering of urokinase in 128 patients with acute myocardial infarction at elementary hospital
LIU Yong,LIU Yan-li,ZHOU Yong-li,ZHAO Hong-lei.Thrombolysis therapy by intravenous administering of urokinase in 128 patients with acute myocardial infarction at elementary hospital[J].South China Journal of Cardiovascular Diseases,2011,17(3):218-220.
Authors:LIU Yong  LIU Yan-li  ZHOU Yong-li  ZHAO Hong-lei
Institution:LIU Yong,LIU Yan-li,ZHOU Yong-li,ZHAO Hong-lei (1.Department of Medicine,Qiaotou Hospital of Dongguan,Dongguan Guangdong 523323,China,2.Department of Cardiology,The People's Hospital of Dongguan,Dongguan Guangdong 523538,China)
Abstract:Objectives To investigate the clinical effect of urokinase for treating acute myocardial infarction(AMI).Methods One hundred and twenty eight patients with AMI underwent thrombolysis therapy by intravenous administering of urokinase were enrolled by retrospective analysis.They were assigned to three groups according to the time of morbidity:inner 3 hours group,3 to 6 hours group and 6 to 12 hours group.The recanalization rate after thrombolysis therapy were compared among the 3 groups.Results The total reca...
Keywords:myocardial infarction  urokinase  thrombolysis therapy  recanalization  
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