| 肝细胞生长素治疗重症肝炎及其机理的研究 |
| |
| 引用本文： | 董祥家,苏德元.肝细胞生长素治疗重症肝炎及其机理的研究[J].中国医科大学学报,1992,21(2):135-138. |
| |
| 作者姓名： | 董祥家 苏德元 |
| |
| 作者单位： | 中国医科大学附属第二医院重症肝炎协作组，中国医科大学附属第二医院重症肝炎协作组，中国医科大学附属第二医院重症肝炎协作组，中国医科大学临床流行病学教研室 |
| |
| 摘 要： | 作者用肝细胞生长素(HGF)治疗重症肝炎44例,并以胸腺肽,胰高血糖素-胰岛素为对照观察。结果,治疗组病死率为31.8％。对照组病死率为47％及44.4％。HGF可降低重症肝炎的病死率。同时发现,HGF可增强重症肝炎血清再生因子的活性,降低血中肿瘤坏死因子的活性,减轻对Na~ —K~ ATP酶的抑制,促进肝细胞再生,减轻脑水肿。
|
| 关 键 词： | 重症病毒性肝炎 肝细胞生长素 治疗 |
HEPATOCYTE GROWTH FACTOR IN THE TREATMENT OF FULMINANT VIRAL HEPATITIS AND ITS' TP ERAPEUTIC MECHANISM |
| |
| Dong Xiangiia,et al.HEPATOCYTE GROWTH FACTOR IN THE TREATMENT OF FULMINANT VIRAL HEPATITIS AND ITS'' TP ERAPEUTIC MECHANISM[J].Journal of China Medical University,1992,21(2):135-138. |
| |
| Authors: | Dong Xiangiia |
| |
| Abstract: | Forty-four cases of fulminant viral hepatitis (FVH) were treated by hepatocyte growth factor (HGF). As control 73 cases of FVH were treated by thymosin and 18 cases by glucagon-insulin therapy. The result showed that the case fatality rate in treatment group was 31.8% and it was 47% and 44.4% in control group. The case fatality rate of FVH decreased in HGF therapy. The study of therapeutic mechanism showed that HGF can increase activity of serum growth factor in patients with FVH and decrease activity of tumor necrcsis factor. |
| |
| Keywords: | fulminant viral hepatitis hepatocyte growth factor treatment |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
