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速效去痛霜对离体小鼠皮透皮吸收作用的研究
引用本文:常天辉,方灵武.速效去痛霜对离体小鼠皮透皮吸收作用的研究[J].中国医科大学学报,1992,21(1):18-20.
作者姓名:常天辉  方灵武
作者单位:中国医科大学药理学教研室 (常天辉,王玉萍),通化206医院药局 (方灵武,刘元秀),通化卫校药理组 (程炳香),沈阳245医院妇产科(徐维清)
摘    要:采用分光光度法及离体小鼠皮的透皮吸收实验,重点观察了速效去痛霜的透皮吸收情况。结果表明,该药透皮吸收效果较好,随时间延长,透皮率逐渐增加。氮酮对该药的透皮吸收有明显促进作用。

关 键 词:双氯灭痛  皮肤  吸收  分光光度法  氮酮

EFFECTS OF SU XIAO QU TONG SHUANG ON PENETRATION OF ISOLATED MOUSE SKIN
Chang Tianhui,et al.EFFECTS OF SU XIAO QU TONG SHUANG ON PENETRATION OF ISOLATED MOUSE SKIN[J].Journal of China Medical University,1992,21(1):18-20.
Authors:Chang Tianhui  
Institution:Dept. of Pharmacology
Abstract:The penetration of Su Xiao Qu Tong Shuang (SXQTS), a dermatologic preparation with a potent analgesic anti-inflammatory effect was studied in isolated mouse skin by spectrophotometry. The results showed that SXQTS had an effective penetrating action through the skin. The ratio of penetrance showed a marked time-dependent relationship.Azone, a component of SXQTS, could facilitate the drug tested to penetrate through the skin.
Keywords:diclofenac sodium  skin  absorption  spectrophotometry  azone
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