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正交试验优选十味桂芪真武颗粒水提工艺
引用本文:张荣嘎,吴勇,王雷,陈卫东. 正交试验优选十味桂芪真武颗粒水提工艺[J]. 蚌埠医学院学报, 2015, 40(1): 110-113. DOI: 10.13898/j.cnki.issn.1000-2200.2015.01.037
作者姓名:张荣嘎  吴勇  王雷  陈卫东
作者单位:1. 安徽中医药大学 药学院, 安徽 合肥 230031;2. 安徽省马鞍山市十七冶医院 药剂科, 243000;3. 安徽省马鞍山市食品药品检验所, 243000
基金项目:安徽省高校省级自然科学研究重点资助项目
摘    要:目的:优选十味桂芪真武颗粒的水提工艺.方法:采用正交设计,以黄芪甲苷、芍药苷的含量和得膏率为指标,考察溶剂量、提取时间以及提取次数对提取结果的影响,筛选最佳提取工艺.结果:最佳提取工艺参数为:加6倍水,煎煮3次,每次1 h.结论:优选的提取工艺切实可行.

关 键 词:中草药   十味桂芪真武颗粒   黄芪甲苷   芍药苷   正交设计
收稿时间:2013-10-01

Optimization of water extraction process for preparing Shiwei Guiqi Zhenwu granules by orthogonal design
ZHANG Rong-ga,WU Yong,WANG Lei,CHEN Wei-dong. Optimization of water extraction process for preparing Shiwei Guiqi Zhenwu granules by orthogonal design[J]. Journal of Bengbu Medical College, 2015, 40(1): 110-113. DOI: 10.13898/j.cnki.issn.1000-2200.2015.01.037
Authors:ZHANG Rong-ga  WU Yong  WANG Lei  CHEN Wei-dong
Affiliation:1. Pharmacy Collelge, Anhui University of Traditional Chinese Medicine, Hefei Anhui 230038;2. Department of Pharmacy, Maanshan Shiqiye Hospital, Maanshan Anhui 243000;3. Maanshan Institute for Food and Drug Control, Maanshan Anhui 243000, China
Abstract:Objective:To establish an optimal extraction process for Shiwei Guiqi Zhenwu granules.Methods:The yield of dry extract and the extraction rates of astragaloside A and paeoniflorin were used as the indices;the orthogonal design was used to investigate the influence of the solvent volume extraction time and extraction frequency on the extraction results.Results:The best extraction process was adding 6 times of water and decocting three tiwes, 1 hour each time.Conclusions:The optimal extraction process is feasible and reliable.
Keywords:Chinese traditional drug  Shiwei Guiqi Zhenwu granules  astragaloside A  paeoniflorin  orthogonal design
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