血型不规则抗体8884例检测结果分析

目的:分析血型不规则抗体阳性患者选择相合的血液输注结果,为避免输血反应的发生提供依据.方法:采用微柱凝胶法对8 884例患者进行抗体筛查,发现阳性标本再用谱细胞进行抗体特异性鉴定.结果:8 884例患者共检出血型不规则抗体阳性85例,阳性率0.96%;其中男性阳性率0.75%,女性阳性率1.04%,差异无统计学意义(P>0.05);有输血史和/或妊娠史者阳性率1.17%,无输血史和妊娠史者阳性率0.52%,2组差异有统计学意义(P<0.01).结论:血型不规则抗体阳性率女性高于男性,有输血史和/或妊娠史高于无输血史和妊娠史者.为确保输血安全,输血前应常规筛查血型不规则抗体.

Analysis of the irregular antibodies detection in 8 884 patients

Objective:To analyze the blood transfusion results of the patients with irregular antibodies, and provide the basis for avoiding hemolytic reaction.Methods:The antibodies of 8 884 patients were screened using the micro-column gel method, and the specificity of the positive samples were identified with panel cell.Results:Among 8 884 patients, 85 cases with positive irregular antibodies were found, the positive rate of which was 0.96%.The positive rates in male and female were 0.75% (19/2530) and 1.04% (66/6354), respectively.The positive rates in the patients with transfusion history or pregnancy history and without transfusion history and without pregnancy history were 1.17%(70/5980) and 0.52% (15/2904), respectively, the difference of which was statistically significant (P<0.01).Conclusions:The positives rates of irregular antibodies in female and the patients with transfusion history or pregnancy history are higher than that in male and the patients without transfusion history and pregnancy history.The screening of irregular antibody before transfusion can ensure its security.