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正交试验法优选保肝醒酒胶囊水煎工艺
引用本文:魏琴,李平,李红卫,唐海风.正交试验法优选保肝醒酒胶囊水煎工艺[J].中国药师,2007,10(10):967-969.
作者姓名:魏琴  李平  李红卫  唐海风
作者单位:1. 兰州大学第二医院,兰州,730030
2. 兰州大学药学院
摘    要:目的:优选保肝醒酒胶囊的水煎工艺。方法:以浸膏得率和总绿原酸含量为指标,采用L_9(3~4)正交试验进行优选。结果:水煎工艺影响因素依次是:煎煮次数>煎煮时间>加水量,最佳制备条件为加12倍的水,煎煮3次,每次0.5 h。结论:该优化的制备工艺易于操作,合理可行。

关 键 词:正交试验  保肝醒酒胶囊  水煎工艺
文章编号:1008-049X(2007)10-0967-03
修稿时间:2007-01-10

Study on Water Extraction Process of Baogan Xingjiu Capsule by Orthogonal Test
Wei Qin,Li Ping,Li Hongwei,Tang Haifeng.Study on Water Extraction Process of Baogan Xingjiu Capsule by Orthogonal Test[J].China Pharmacist,2007,10(10):967-969.
Authors:Wei Qin  Li Ping  Li Hongwei  Tang Haifeng
Institution:1. Affiliated Second Hospital of Lanzhou University, Lanzhou 730030, China;2.Pharmacy College of Lanzhou University
Abstract:Objective:To study the optimum water extracting process of Baogan Xingjiu Capsule.Method:The extract yield of chlorogenic acid and extractum were used as detective target,the extraction process was studied by orthogonal design of L_9(3~4).Re- sult:The affecting factors of water extraction process were described as:boiling times>boiling duration>added water volume.The optimum extracting conditions were adding twelve times water and boiling extraction for three times with 0.5 hours every time.Conclu- sion:The process is reasonable,practicable and convenient.
Keywords:Orthogonal test  Baogan Xingjiu Capsules  Water extraction process
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