| 蜂胶提取液生物安全性的初步评价 |
| |
| 引用本文： | 马丁,和红兵,吴恩格. 蜂胶提取液生物安全性的初步评价[J]. 实用口腔医学杂志, 2007, 23(1): 71-74 |
| |
| 作者姓名： | 马丁 和红兵 吴恩格 |
| |
| 作者单位： | 1. 昆明医学院口腔学院,650031
2. 昆明医学院附属口腔医院 |
| |
| 摘 要： | 目的:对自行研制的300g/L蜂胶提取液的生物安全性进行初步的评价。方法:根据中华人民共和国医药行业标准,应用体外细胞培养琼脂覆盖法对这种蜂胶提取液进行细胞毒性评价。利用大耳白兔检测这种蜂胶提取液对口腔黏膜的刺激反应。结果:该蜂胶提取液的细胞毒性分级为0级;口腔黏膜刺激试验中实验动物未见局部及全身的不良刺激反应。结论:该蜂胶提取液不具有细胞毒性及对口腔黏膜的不良刺激反应。
|
| 关 键 词： | 蜂胶 细胞毒性试验 口腔黏膜刺激试验 |
| 文章编号： | 1001-3733(2007)-01-0071-03 |
| 修稿时间： | 2006-05-10 |
Preliminary evaluation of the biocompatibility of a liquid abstract of propolis |
| |
| Ma Ding,He Hongbing,Wu Enge. Preliminary evaluation of the biocompatibility of a liquid abstract of propolis[J]. Journal of Practical Stomatology, 2007, 23(1): 71-74 |
| |
| Authors: | Ma Ding He Hongbing Wu Enge |
| |
| Affiliation: | College of Stomatology, Kunming Medical College, Kunming 650031, China |
| |
| Abstract: | Objective:To evaluate the biocompatibility Abstract of a liquid of propolis. Methods:According to the relative Chinese national standards,the cytotoxicity of the propolis abstract was investigated by in vitro cell culture,agar diffusion test and the oral mucous membrane irritation response test in rabbits. Results:In the in vitro tests the propolis abstract showed grade 0 cytotoxicity. In the in vivo test the abstract did not result in any pathological change in oral mucous membrane.Conclusion:The propolis abstract is biocompatible. |
| |
| Keywords: | Propolis Cytotoxicity Oral mucous membrane irritation test |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
