莫沙必利联合思连康治疗功能性消化不良的疗效观察

目的：观察莫沙必利联合思连康治疗功能性消化不良的临床疗效。方法：选择2006年1月～2009年4月功能性消化不良患者152例,随机分为治疗组和对照组。治疗组76例采用枸橼酸莫沙必利分散片5mg,每日3次;思连康1.5g,餐后用50℃以下温水或牛奶送服,3次/d。对照组采用多潘立酮片10mg,每日3次口服。结果：治疗组显效率为59.2%、总有效率为88.2%,对照组显效率为25.0%、总有效率为63.2%,两组间有非常显著性差异（P〈0.01）。治疗结束后1年,治疗组复发率为7.5%,对照组复发率为33.3%,两组复发率比较,有非常显著性差异（P〈0.01）。结论：莫沙必利联合思连康治疗功能性消化不良的疗效明显,安全可靠。

Efficacy observation of Mosapride combined with Siliankang in the treatment of functional dyspepsia

Objective：To observe the clinical effect of Mosapride combined with Siliankang in the treatment of functional dyspepsia.Methods：152 patients of functional indigestion were selected and randomly divided into treatment group and control group.76 cases in treatment group used Mosapride Citrate 5 mg dispersible tablet,3 times a day;Siliankang 1.5 g with 50 degrees below the water or milk pills after the meal,3 times a day.76 cases in control group used Domperidone Tablets 10 mg,3 times a day.Results：The obvious effective rate of treatment group was 59.2%,the total effective rate was 88.2%,the obvious effective rate of control group was 25.0%,the total effective rate was 63.2%,there was very significant difference between two groups（P〈0.01）.One year after treatment,the recurrence rate of treatment group was 33.3% and the control group was 7.5%,there was very significant difference between two groups（P〈0.01）.Conclusion：The curative effect of Mosapride combined with Siliankang in the treatment of unctional dyspepsia is significantly,safe and reliable.