| α-L-岩藻糖苷酶对原发性肝癌诊断价值的探讨 |
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| 引用本文： | 赵平,王江滨,张爱国,王广.α-L-岩藻糖苷酶对原发性肝癌诊断价值的探讨[J].临床肝胆病杂志,2003,19(2):109-110. |
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| 作者姓名： | 赵平 王江滨 张爱国 王广 |
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| 作者单位： | 中日联谊医院消化内科,长春,130031 |
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| 摘 要： | 探讨α－L－岩藻糖苷酶（alpha-L-fucosidase AFU)对原发性肝癌的诊断价值。分别采用放免法和显色多肽基质法对93例原发性肝癌、45例恶性肿瘤，98例良性肝病、46名孕产妇及20例正常健康人的血清中甲胎蛋白（alpha-fetoprotein AFP)水平和AFU活性进行联合检测。原发性肝癌组血清AFP水平及AFU活性明显高于其它各疾病组。AFU和AFP对原发性肝癌诊断的敏感性分别为76．3％和74．2％，在AFP阴性肝癌患者中AFU阳性率为75．0％。AFU，AFP两者联合检测诊断原发性肝癌的敏感性可提高到93．5％。
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| 关 键 词： | α－L－岩藻糖苷酶 甲胎蛋白 原发性肝癌 肝硬化 |
| 文章编号： | 1001-5256(2003)02-0109-02 |
| 修稿时间： | 2002年2月27日 |
Study on the diagnostic value of α-L-fucosidase on primary hepatic carcinoma |
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| ZHAO Ping,WANG Jiang - bin,ZHANG Ai - guo,et al..Study on the diagnostic value of α-L-fucosidase on primary hepatic carcinoma[J].Chinese Journal of Clinical Hepatology,2003,19(2):109-110. |
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| Authors: | ZHAO Ping WANG Jiang - bin ZHANG Ai - guo |
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| Abstract: | To discuss the diagnostic value of a - L - fucosidase on primary hepatic carcinoma. Serum levels between AFU and AFP were measured in patients with PHC (93 cases) , malignant tumor (45 cases) , benign liver disease (98 cases) , gravida and puer-perant (46 cases) and healthy (20 cases) . The levels of AFU and AFP in PHC groups was significant different from other groups. The sensitivity of AFU and AFP is 76.3% and 74.2% ,The positive rate of AFU in AFP - negative PHC group is 75.0% . The sensitivity can be increased to 93.0% when AFU and AFP were combining detected. |
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