雌性小鼠生殖系统、垂体和大脑中孕酮受体的免疫细胞化学研究

应用免疫细胞化学ＬＳＡＢ法和孕酮受体抗体研究了雌性小鼠生殖系统、垂体和大脑中孕酮受体的分布及其与胚泡植入的关系。结果：孕酮受体主要分布于子宫和阴道，输卵管中含量极少。它们均位于细胞核内，胞质为阴性。卵巢、垂体和大脑未见阳性反应细胞。孕酮受体在子宫内膜表面上皮和间质中的含量变化与胚泡植入平行发展。结果提示：子宫内膜在为胚泡植入做准备的过程中与孕酮受体的关系密切。

Immunocytochemistry of Progesterone Receptors in Reproductive System,Pituitary Gland and Cerebrum of Female Mice

Progesterone receptors in reproductive system (including ovary,fallopian tube,uterus and vagina),pituitary gland and cerebrum of female mice were studied by immunocytochemical LSAB method in order to show the distribution of receptors and the relationship between the receptors and blastula implantation.Progesterone receptors distributed mainly in uterus and vagina,and only a few in fallopian tube.The receptors were located in nuclei, but not in cytoplasm.No positive reaction could be detected in ovary, pituitary gland and cerebrum.The amount changes of the receptors in the endometrial epithelium and the uterine stroma were consistent with the development of blastula implantation.These data suggest that the progesterone receptors are closely related with the endometrial preparation for blastula implantation.