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胰腺实性假乳头状瘤临床病理分析
引用本文:周莉,屈重霄,亢姝娇. 胰腺实性假乳头状瘤临床病理分析[J]. 实用医技杂志, 2008, 15(14): 1819-1821
作者姓名:周莉  屈重霄  亢姝娇
作者单位:1. 泰山医学院附属聊城市第二人民医院,山东,临清,252600
2. 山西省人民医院,山西,太原,030012
3. 赤峰市中心医院,内蒙古,赤峰,024000
摘    要:目的:探讨胰腺实性一假乳头状瘤(SPTP)的临床病理学及免疫组化特点。方法:4例SPTP作HE、免疫组织化学((PV2000法)染色观察。结果:4例SPT中3例为女性,1例男性,年龄15岁~36岁,平均年龄27岁,术后均无复发。肿瘤体积较大,平均直径8.6cm,有包膜,囊实性相间。镜检,肿瘤由乳头和囊实区混合组成,细胞形态一致,核圆或卵圆,异型不明显,核分裂象罕见。瘤细胞围绕纤维血管轴心形成特征性假乳头结构。1例侵犯胰腺周围组织。多数肿瘤表达vimentin,a-AT,a-ACT,部分表达Syn,CgA,PR和AE1/AE3,EMA,ER均阴性。结论:胰腺SPTP好发年轻女性,具有独特的临床病理特点,手术切除治愈率高,应视为低度恶性肿瘤,免疫组化提示可能起源于胰腺多能干细胞。

关 键 词:胰腺肿瘤  免疫组织化学  预后

Solid Pseudopapillary Tumor of the Pancreas Aclinicopathologic Analysis of 4 Cases
ZHOU Li,QU Chong-xiao,KANG Shu-jiao. Solid Pseudopapillary Tumor of the Pancreas Aclinicopathologic Analysis of 4 Cases[J]. Journal of Practical Medical Techniques, 2008, 15(14): 1819-1821
Authors:ZHOU Li  QU Chong-xiao  KANG Shu-jiao
Affiliation:ZhOU Li1; QU Chong-xiao2; KANG Shu-jiao3(1.The Second People s Hospital of Taishan Medical College in Liaocheng; Linqing; Shandong; 252600; China; 2.The People s Hospital of Shanxi; Taiyuan; Shanxi; 030012; 3.The Central Hospital of Chifeng; Chifeng; Neimenggu; 024000; China);
Abstract:Objective To study the clinicopathologic and immunohistochemical characteristics of solid pseudopapillary neoplasm of pancreas(SPTP).Methods 4cases of SPTP were studied by using histologic HE and immunohistochemistry(PV2000 method).Results There were 3 female and 1 male patients aged from 15 to 36(mean age 27)in our cases that had no recurrence after resection.Those tumorswere larger in size(mean diameter of 8.6 cm),solid alternately with cystic andcircumscribed by capsule.Histologically,they were composed ...
Keywords:Pancreatic neoplasms  Immunohistochemistry  Prognosis
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