| 豫北地区727例不孕不育患者染色体分析 |
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| 引用本文： | 李佳佳,徐振平,朱春辉,秦晨,张艳瑞,孙璐. 豫北地区727例不孕不育患者染色体分析[J]. 新乡医学院学报, 2011, 28(5): 590-591 |
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| 作者姓名： | 李佳佳 徐振平 朱春辉 秦晨 张艳瑞 孙璐 |
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| 作者单位： | 新乡医学院生命科学技术系； 新乡医学院遗传与基因工程教研室； 新乡医学院国际教育学院； 新乡医学院形态学实验室； |
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| 基金项目： | 新乡医学院大学生科研课题(2009) |
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| 摘 要： | 目的通过对豫北地区727例不孕不育患者进行染色体分析,探讨染色体异常与不良孕产之间的关系。方法外周血淋巴细胞培养,常规G显带制片后进行染色体核型分析。结果 727例不孕不育患者中异常核型39例,异常检出率5.36%,其中常染色体异常16例,占41.03%;性染色体异常22例,占56.41%;两性畸形1例,占2.56%。结论染色体异常是导致不孕不育不可忽略的因素,在高危人群中进行产前染色体检查,对指导优生优育有积极的作用。
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| 关 键 词： | 不孕不育 染色体异常 核型分析 |
Analysis of chromosome of 727 patients with infertility in north of Henan |
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| LI Jia-jia,XU Zhen-ping,ZHU Chun-hui,QIN Chen,ZHANG Yan-rui,SUN Lu. Analysis of chromosome of 727 patients with infertility in north of Henan[J]. Journal of Xinxiang Medical College, 2011, 28(5): 590-591 |
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| Authors: | LI Jia-jia XU Zhen-ping ZHU Chun-hui QIN Chen ZHANG Yan-rui SUN Lu |
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| Affiliation: | LI Jia-jia1,XU Zhen-ping2,ZHU Chun-hui1,QIN Chen3,ZHANG Yan-rui3,SUN Lu4(1.Grade 2007,Department of Life Science and Technology,Xinxiang Medical College,Xinxiang 453003,Henan Province,China,2.Department of Genetics and Genetic Engineering,3.International Education Institute,4.Morphological Laboratory,China) |
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| Abstract: | Objective By analyzing the chromosome karyotype of 727 patients with infertility,and the relationship between chromosome abnormality and infertility was explored. Methods The peripheral blood lymphocytes were cultured,and chromosome karyotype was analyzed after conventional G-banding. Results There were 39 abnormal cases in 727 inspected cases,accounting to 5.36%.There were 16 euchromosome abnormal cases,22 heterosome cases and 1 hermaphroditism cases among the 39 cases,which relevance ratio was 41.03%,56.4... |
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| Keywords: | infertility chromosome aberration karyotype analysis |
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