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卵巢癌患者手术治疗前后血清CEA、CA125和IL-8联检的临床意义
引用本文:张春艳,周东霞,王恩波,张树敏.卵巢癌患者手术治疗前后血清CEA、CA125和IL-8联检的临床意义[J].放射免疫学杂志,2008,21(6):546-547.
作者姓名:张春艳  周东霞  王恩波  张树敏
作者单位:1. 江苏省沐阳县人民医院妇产科,223600
2. 连云港市第一人民医院
摘    要:目的:探讨了卵巢癌患者手术治疗前后血清CEA、CA125和IL-8水平的变化及意义。方法:应用放射免疫分析和酶联免疫分析对32例卵巢癌患者进行了手术治疗前后血清CEA、CA125和IL-8检测,并与35名正常健康人作比较。结果:在手术治疗前卵巢癌患者CEA、CA125和IL-8水平非常显著地高于正常人组(P〈0.01),经手术治疗6个月后则与正常人比较无显著性差异(P〉0.05)。结论:检测血清CEA、CA125和IL-8水平的变化对观察病情和预后判定均具有重要的临床价值。

关 键 词:卵巢癌  癌胚抗原  糖类抗原-125  白细胞介素-8

Clinical Significance of Combined Determination of Changes of Serum CEA,CA125 and IL-8 Levels After Operation in Patients with Ovarian Cancer
Zhang Chunyan,Zhou Dongxia,Wang Enbo,et al..Clinical Significance of Combined Determination of Changes of Serum CEA,CA125 and IL-8 Levels After Operation in Patients with Ovarian Cancer[J].Journal of Radioimmanology,2008,21(6):546-547.
Authors:Zhang Chunyan  Zhou Dongxia  Wang Enbo  
Institution:Zhang Chunyan,Zhou Dongxia,Wang Enbo,et al.Department of Obsteric , Gynecology,Shuyang County People\'s Hospital,Shuyang,Jiangsu(223600)
Abstract:Objective To explore the changes of serum CEA,CA125 and IL-8 levels both before and after operation in patients with ovarian cancer.Methods Serum CEA,CA125 and IL-8(with RIA) and IL-8(with ELISA) levels were measured in 32 patients with ovarian cancer both before and after operation as well as in 35 controls.Results Before operation the serum CEA,CA125 and IL-8 levels were significantly higher in the patients than those in the controls(P<0.01).Six months after operation the levels were not significantly dif...
Keywords:ovaricn cancer  carcinoembryonic antigen(CEA)  carbo hydrate antigen 125(CA125)  interluekin-8(IL-8)  
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