骨巨细胞瘤影像学

骨巨细胞瘤是一种常见的骨原发性肿瘤，本文通过对文献的复习，系统地介绍骨巨细胞瘤的临床、病理、X线、CT和MRI的表现特点，认为骨巨细胞瘤的影像学表现有一定的特征性，典型的X线表现为长管骨骨端偏心性、膨胀性、皂泡样、达关节软骨下骨边界清楚的溶骨性骨质破坏；典型的CT表现为骨端偏心性、膨胀性、溶骨性骨质破坏，骨皮质变薄，连续性完整或栅栏状中断，肿瘤的边缘可有程度不等、断续的骨质硬化，肿瘤内可见有短小的骨嵴；典型的MRI表现为长骨骨端偏心性、达关节软骨下骨的异常信号区，T1WI为中等信号，T2WI为中、高信号混杂，可出现液一液平，肿瘤的边缘有一相对比较规则的、由于周围骨质硬化引起的T1WI及T2WI均为低信号的线状影；影像学检查对于骨巨细胞瘤的诊断、鉴别诊断及治疗后随访均有重要的价值。

Imageology of Giant Cell Tumor of Bone

Giant cell tumor of bone (GCT) is an common primary neoplasm of bone. We systemically introduce the features of GCT in clinic, pathology, radiography, CT and MR images. We found the GCT had a quite characteristic appearance, the common location was in the epiphyseal ends of long tubular bones, the common radiographic features were eccentric, expanded, lytic, multicocular or trabeculated, welldefined lesion , which has a narrow zone of transition, thinned cortex and approaches the adjacent subarticular cortex, most of cases had no periosteal reaction; The common features in CT scans were also eccentric, expanded, lyric lesion, which has a thinned cortex, cortical breakthrough in different degree, a irregular peripheral sclerosis and trabeculation; The common features in MR imaging were intermediate signal intensity on T1WI, intermediate to high or mixed signal intensity on T2WI, normaly with a band of low signal intensity attributed to marginal scleroses, occasionally with liquid- liquid level. To the GCT, imaging is useful in diagnosis, differentiation, follow - up after the treatment.