白质病变与血管性认知障碍的相关研究

目的探讨白质病变与血管性认知障碍及其相关危险因素的关系,为血管性痴呆的预防、早期诊断和治疗提供理论依据。方法选择130例经影像学证实的白质病变患者,经简易智能状态检查量表(MMSE)评估分为认知障碍组和无认知障碍组,分别对白质病变部位和分级进行比较。结果室周病变、室周合并深部白质及弥漫性白质病变与认知障碍相关。结论白质病变对血管性认知障碍的发生有显著影响。

Study on the correlation between white matter lesion and vascular cognitive disorder

Objective It is to explore the relationship between white matter lesion and vascular cognitive disorder and its correlated dangerous factors,so to provide theory evidence for the prevention,early diagnosis and treatment for vascular dementia.Methods 130 patients with white matter lesion diagnosed by imageology were chosen and divided into cognitive disorder group and no cognitive disorder group by MMSE scores.The diseased region and degree were compared between the two groups. Results Pathological changes of cerebral ventricle periphery,pathological changes of cerebral ventricle periphery complicating with deep or diffusibility white matter lesion were related with cognitive disorder.Conclusion White matter lesion has a significant effect on the occurrence of vascular cognitive disorder.