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Adult polycystic kidney disease and linked RFLPs at the alpha globin locus: a genetic study in the South Wales population.
Authors:L P Lazarou  F Davies  M Sarfarazi  G A Coles  and P S Harper
Abstract:Thirteen South Wales kindreds with adult polycystic kidney disease have been studied for genetic linkage using the alpha globin and 3'HVR probes. A maximum lod score of 24.187 was found at a recombination fraction of 0.03. This study supports the existence of a single locus on chromosome 16 responsible for the disorder.
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