外阴癌转移复发分析

目的:总结影响外阴癌预后、转移复发的相关因素,探讨理想的治疗方法。方法:分析本院1970年1月至2000年1月收治的162例外阴癌,比较不同治疗方法、分期以及不同复发时间、部位对5年生存率的影响。结果:162例患者总的5年生存率为60.5%,其中外阴鳞癌5年生存率为68.7%。复发率为34.3%,复发部位单纯外阴占40.0%,腹股沟淋巴结占42.2%,盆腔淋巴结转移占6.7%,远处转移11.1%。结论:外阴癌复发者外阴白斑发病比例高于未复发者(P<0.05),复发部位是影响预后的重要因素,2年内复发者预后差。外科手术是影响外阴局部复发的主要因素。

Analysis of Metastasis and Recurrence of Carcinoma of the Vulva

Objective: To evaluate the optimal treatment and outcome of recurrent vulvar cancer. Methods: In a retrospective review of 162 cases with vulvar carcinoma between 1970 and 2000, there was an incidence rate of 2.9% of all female genital neoplasms. The different surgical strategies and various prognostic factors affecting recurrence were compared. Results: The overall 5-year survival of vulvar squamous cancer was 68.7% (90/131). The recurrence rate was 34.3% (45/131). Distribution of recurrence was as follows: 40.0% in the vulva, 42.2% in the inguinal region, 6.7% in the pelvic cavity and 11.1% as distant metastases. Conclusion: The rate of morbidity due to leukoplakia vulvae in the recurrent cases is higher than that of patients without recurrence (P<0.05). The physical location of the recurrence is an important factor affecting the prognosis. The prognosis is poor for those suffering recurrence within 2 years. Surgical intervention is the main treatment for decreasing the incidence of local recurrence of carcinoma of the vulva.