光明、太冲穴与中枢神经相关效应的观察

目的:观察针刺光明、太冲穴时,中枢不同区域的相关反应.方法:将19名正常志愿者随机分为1组(视觉刺激加单侧针刺组)7人,2组(视觉刺激加双侧针刺组)6人和3组(单纯针刺双侧穴组)6人.用功能性磁共振(fMRI)观察各组在针刺光明、太冲穴时视觉皮质区与相关脑区的反应.结果:发现视觉刺激及针刺进针时,视觉皮质的血氧饱和水平(BOLD)无明显变化(P＞0.25),但在进行单侧和双侧持续刺激时,发现大脑相关区域有BOLD变化.结论:针刺对单侧和双侧穴位的刺激均能改善大脑相关区域的BOLD,但与进行手法和视觉刺激无关.

Observation on relation of acupuncture at Guangming (GB 37) and Taichong (LR 3) with central nervous reaction

OBJECTIVE: To observe relative effects of acupuncture at Guangming (GB 37) and Taichong (LR 3) in central different regions. METHODS: Nineteen healthy volunteers were randomly divided into 3 groups: group I (n=7) received visual stimulation and acupuncture at one side; group II (n=6) received visual stimulation and acupuncture at both sides; and group III (n=6) received acupuncture at both sides. Functional magnetic resonance imaging (fMRI) was used to investigate reactions of the different visual cortexes and relative cerebral regions in acupuncture at Guangming (GB 37) and Taichong (LR 3). RESULTS: There was no significant change in blood oxygen saturation levels in the visual cortex at visual stimulation and insertion of the needle, but there were changes in blood oxygen saturation level in relative cerebral regions when continuous stimulation was given to one-side or both sides. CONCLUSION: Acupuncture at one-side or both sides can improve blood oxygen saturation level in relative cerebral regions, which is not related with manipulation method and visual stimulation.