|
|||||
|
|
Discovery of WAY-260022, a Potent and Selective Inhibitor of the Norepinephrine Transporter |
||
| Authors: | Lori K Gavrin Paige E Mahaney Douglas Jenkins Lisa M Nogle Cheryl A Mugford Christine Huselton Jennifer Leiter Grace H Johnston Jenifer A Bray Kevin D Burroughs Scott A Cosmi Peter Alfinito Douglas M Ho Darlene C Deecher Eugene J Trybulski | |
| Institution: | †Worldwide Medicinal Chemistry, Pfizer Global Research and Development, 200 Cambridge Park Drive, Cambridge, Massachusetts 02140;‡Worldwide Medicinal Chemistry;§Drug Safety and Metabolism;∥Women''s Health and Musculoskeletal Biology;Pfizer Global Research and Development, 500 Arcola Road, Collegeville, Pennsylvania 19426;⊥Department of Chemistry, Princeton University, Princeton, New Jersey 08544 | |
| Abstract: | ||
| Keywords: | WAY-260022 norepinephrine reuptake inhibitor serotonin transporter dopamine transporter brain penetration vasomotor symptoms | |