负压伤口治疗在假体乳房再造术后并发症的预防和治疗的应用现状和研究进展

假体乳房再造是乳腺癌术后乳房再造方式的主流，然而再造术后切口愈合不良、组织感染等并发症不仅增加医疗成本、影响美观，严重者还将导致假体缺失、乳房再造失败，极大地影响患者的生活质量。随着负压技术的进步，闭合切口负压治疗和负压联合滴注疗法被证明在预防和治疗假体乳房再造术后并发症方面具有显著优势，但其确切机制和使用负压技术的最佳条件及选择仍不清楚。本文从闭合切口负压治疗（ciNPWT）、负压滴注疗法（NPWTi-d）的应用现状与机制研究方面进行全面而系统的综述。

Application status and research progress of negative pressure wound therapy in the prevention and treatment of complications after prosthesis-based breast reconstruction

Prosthesis-based breast reconstruction is the mainstream of breast reconstruction after breast cancer surgery. However, postoperative complications such as poor incision healing and tissue infection after breast reconstruction not only increase medical costs and affect aesthetics but also lead to prosthesis loss and even breast reconstruction failure in severe cases, which significantly affect the quality of life of patients. With the progress of negative pressure technology, closed incision negative pressure therapy (ciNPWT) and negative pressure wound therapy with instillation and dwell (NPWTi-d) have been proven to have significant advantages in preventing and treating complications after prosthesis-based breast reconstruction. At the same time, the exact mechanism, the optimal conditions, and selection of negative pressure technology are still unclear. This review provides a comprehensive and systematic review of the application status and mechanism research of ciNPWT and NPWTi-d.