| 他莫昔芬相关眼部病变的研究进展 |
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| 引用本文： | 王萌,马瑾,钟勇. 他莫昔芬相关眼部病变的研究进展[J]. 中华眼科杂志, 2021, 0(3): 232-236 |
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| 作者姓名： | 王萌 马瑾 钟勇 |
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| 作者单位： | 中国医学科学院 |
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| 摘 要： | 本文回顾总结了近年来他莫昔芬应用于乳腺癌、神经胶质瘤治疗时出现的相关眼部病变的文献，将他莫昔芬导致眼部病变出现的发生率、发病机制、相关眼部病变特征性表现（角膜病变、白内障、视网膜病变、视神经病变以及其他一些少见病变）进行综述，为眼科医师对他莫昔芬眼部病变的识别和眼部病变的监测提供指导。 （中华眼科杂志，20...
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| 关 键 词： | 他莫昔芬 视网膜疾病 角膜疾病 白内障 视神经疾病 |
Ocular toxicity induced by tamoxifen:an overview |
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| Wang Meng,Ma Jin,Zhong Yong. Ocular toxicity induced by tamoxifen:an overview[J]. Chinese Journal of Ophthalmology, 2021, 0(3): 232-236 |
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| Authors: | Wang Meng Ma Jin Zhong Yong |
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| Affiliation: | (Department of Ophthalmology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China) |
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| Abstract: | By reviewing the recent articles regarding the ocular side effect of tamoxifen when treating breast cancer and glioma,this article summarized the incidence and the potential mechanism of the side effects of tamoxifen,and the specific ocular toxicity including keratopathy,cataract,retinopathy,optic neuropathy.This review would provide guidance for clinical ophthalmologists to early identify and appropriately manage tamoxifen induced ocular diseases.(Chin J Ophthalmol,2021,57:232-236) |
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| Keywords: | Tamoxifen Retinal diseases Corneal diseases Cataract Optic nerve diseases |
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