江苏省扬中市食管癌高危人群危险因素及其聚集性

  目的  分析江苏省扬中市食管癌高危人群危险因素流行、聚集现状并探讨危险因素聚集的影响因素。  方法  以上消化道癌早诊早治及食管癌专病队列项目为依托，运用多阶段分层整群抽样的方法，抽取扬中市2 591名40~69岁高危人群进行一对一式面访调查，采用单因素Logistic回归分析模型及多因素Logistic回归分析模型探讨危险因素聚集的影响因素。  结果  扬中市食管癌高危人群吸烟、饮酒、烫热饮食摄入、进食过快、室内空气污染、牙齿缺失和危险因素聚集的流行率分别为22.27%、17.79%、16.79%、26.94%、18.45%、32.15%和40.22%。最常见的危险因素聚集模式为室内空气污染+牙齿缺失、吸烟+饮酒和进食过快+牙齿缺失。多因素Logistic回归分析模型分析显示，在男性、年龄大、文化程度低和农村高危人群中危险因素聚集性较高(均有P < 0.05)。  结论  扬中市食管癌高危人群中部分危险因素暴露还处于较高水平且危险因素存在明显的聚集，男性、年龄大、文化程度低和农村地区居民是食管癌防控的重点人群。

Current status and clustering analysis of risk factors in high-risk groups of esophageal cancer in Yangzhong City,Jiangsu Province

Objective To analyze the prevalence and clustering of esophageal cancer risk factors and explore the influencing factors of its clustering among high-risk groups of esophageal cancer in Yangzhong,Jiangsu Province.Methods Relying on the early diagnosis and treatment of upper gastrointestinal cancer and esophageal cancer-specific disease cohort project,we used multi-stage stratified cluster sampling and 2591 high-risk populations aged 40 to 69 years old were selected for a one-to-one interview survey.Univariate Logistic regression analysis and multivariate Logistic regression analysis were used to explore the influencing factors of risk clustering.Results The prevalence rates of smoking,drinking,hot diet intake,eating too fast,indoor air pollution,teeth loss among participants were 22.27%,17.79%,16.79%,26.94%,18.45%,32.15%and 40.22%,respectively.The most common clustering patterns of risk factors were indoor air pollution+teeth loss,smoking+drinking and eating too fast+teeth loss.Multivariate Logistic regression analysis showed that the risk factors clustering was higher among men,older,low-educated,and rural high-risk groups(all P<0.05).Conclusions The exposure of some risk factors among high-risk populations of esophageal cancer in Yangzhong City is still at a relatively high level,and there is an apparent clustering of risk factors.Males,the elder,residents with low education level and in rural areas are the key groups for the prevention and control of esophageal cancer.