中老年人BMI与日常生活活动能力关联

  目的  探究中国中老年人BMI与工具性日常生活活动能力(instrumental activities of daily living, IADL)之间的关系。  方法  本研究基于中国健康与养老追踪调查(China health and retirement longitudinal study, CHARLS)2011-2015年的随访数据，剔除基线存在IADL失能者，最终纳入研究对象8 955名。采用二分类Logistic线性回归分析模型分析BMI与IADL失能发生风险的关联。  结果  经过4年的随访，2 186名(24.41%)研究对象发生IADL失能，其中男性和女性发生率分别为18.79%和29.89%。低体重、正常体重、超重及肥胖组的IADL失能发生率分别为42.64%、25.13%、19.85%和23.49%。与正常体重组相比，低体重、超重及肥胖组IADL失能发生风险的OR值分别为1.381(95% CI: 1.117~1.707, P=0.003)、0.830(95% CI: 0.727~0.948, P=0.006)和0.985(95% CI: 0.819~1.185, P=0.874)。  结论  与正常体重组相比，中老年人群中低体重与IADL失能的发生呈正向关联，而超重则与IADL失能呈负相关关系，肥胖与IADL失能之间不存在统计学意义。

Association of body mass index with activities of daily life among middle-aged and older Chinese

Objective To examine the association between BMI and the incidence of disability assessed by instrumental activities of daily living(IADL)among middle-aged and older Chinese.Methods This study was based on the China health and retirement longitudinal study 2011-2015(baseline to second follow-up visits).After excluding participants with IADL-defined disability at baseline,8955 participants were included in the study.Binary Logistic liner regression model was performed to determine the association bewteen BMI and incidence of IADL-defined disability.Results During 4 years of follow-up,2186(24.41%)participants developed disability(18.79%in men and 29.89%in women).The incidence rates of disability were 42.64%,25.13%,19.85%and 23.49%in the underweight,normal weight,overweight and obesity groups,respectively.Compared with participants with normal weight,the adjusted odds ratio of disability in participants who were underweight,overweight and obese were 1.381(95%CI:1.117-1.707,P=0.003)、0.830(95%CI:0.727-0.948,P=0.006)and 0.985(95%CI:0.819-1.185,P=0.874),respectively.Conclusions Compared with participants with normal weight,underweight was positively associated with risk of disability,and there was an inverse association between overweight and disability,while no significant association was observed between obesity and disability.