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Sensorineural hearing loss in acromegalic patients under treatment
Authors:Marcelo Alexandre Carvalho  Renan Magalhães Montenegro Júnior  Marcos Rabelo de Freitas  Lúcio Vilar  Alessandra Teixeira Bezerra de Mendonça  Renan Magalhães Montenegro
Affiliation:1. Otorhinolaryngologist; MSc in Public Health - Federal University of Ceará;2. Endocrinologist. PhD; Adjunct Professor - Medical School of the Federal University of Ceará;3. Otorhinolaryngologist; PhD; Adjunct Professor - Medical School of the Federal University of Ceará;4. Endocrinologist. PhD; Adjunct Professor - Medical School of the Federal University of Pernambuco;5. Speech and Hearing Therapist - Department of Otorhinolaryngology Walter Cantídio University Hospital - Federal University of Ceará)
Abstract:Acromegaly is a rare endocrine disease. Few studies have evaluated its association with hearing loss (HL) and the results are conflicting.Aim: To evaluate the prevalence and features of HL in a group of patients being treated for acromegaly. To analyze peripheral and central auditory transmission.Methods: Cross-sectional study. A group of 34 patients with acromegaly were submitted to metabolic evaluation, tonal audiometry and brainstem auditory evoked potentials. HL was considered when pure tone average was > 25 DBHL for low frequencies (250, 500, 1000 and 2000 Hz) or high frequencies (3000, 4000, 6000 and 8000 Hz). The patients were divided in group A (with HL) and B (without HL).Results: Twelve patients (35.3%) had sensorineural HL (Group A), being 8 bilateral and 4 unilateral. No one had mixed or conductive HL. The prevalence of diabetes/impaired glucose tolerance was similar between the groups. The frequencies 3000, 4000, 6000 and 8000 Hz were the most affected and with a similar pattern in both ears.Conclusion: sensorineural HL was found in 38.9% of cases. Neither clinical nor metabolic differences were noted between the groups, as well as in regards to peripheral and central auditory transmission.
Keywords:acromegaly  evoked potentials  auditory  brain stem  hearing loss conductive  hearing loss  sensorineural
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