| 卵巢癌患者血浆中Th1/Th2类细胞因子的检测 |
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| 引用本文： | 孔北华,崔保霞,江森.卵巢癌患者血浆中Th1/Th2类细胞因子的检测[J].现代妇产科进展,2000,9(2):104-105. |
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| 作者姓名： | 孔北华 崔保霞 江森 |
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| 作者单位： | 山东医科大学附属医院妇产科,250012 |
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| 摘 要： | 探讨卵巢癌患者血浆中Th1/Th2类细胞因子失调及其临床意义。方法 :用ELISA法检测了 2 5例卵巢癌及 15例健康妇女血浆中IL - 2、IFN -γ、IL - 6和IL - 10水平。结果 :卵巢癌患者较健康妇女血浆中IL - 2水平明显降低 ,而IL - 6和IL - 10明显升高 ,且这种变化随临床期别的升高更加明显。结论 :卵巢癌患者外周血中Th1/Th2类细胞因子失调 ,在卵巢癌的发生发展中可能起重要作用。
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| 关 键 词： | 卵巢肿瘤 细胞因子 Th1/Th2细胞 酶联免疫吸附测定 |
Evaluation of Th1/Th2 type cytokines in plasma of ovarian cancer patients |
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| Kong Beihua,Cui Baoxia,Jiang Sen.Evaluation of Th1/Th2 type cytokines in plasma of ovarian cancer patients[J].Current Advances In Obstetrics and Gynecology,2000,9(2):104-105. |
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| Authors: | Kong Beihua Cui Baoxia Jiang Sen |
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| Abstract: | Objective:WT5BZ]To study the disregulation of Th1/Th2 type cytokines in plasma of ovarian cancer patients Methods:Levels of IFN-γ,IL-2,IL-6 and IL-10 were determined using ELISA in plasma from 25 patients with ovarian cancer and 15 healthy women Results:The plasmatic levels of IL-6 and IL-10 in patients were significantly higher than those in the controls By contrast,the IL-2 plasmatic level was lower As the disease progressed,the levels of IL-6,IL-10 increased whereas IL-2 level decreased Conclusions:There are disregulation of Th1/Th2 type cytokines in peripheral blood of ovarian cancer patients It may play an important role in the pathogenesis and progression of ovarian cancer |
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| Keywords: | Ovarian neoplasms Cytokine Th1/Th2 cells Enzyme-linked immunosorbent assay |
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