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Neurogenic stunned myocardium after embolization in two children with vein of Galen aneurysmal malformation
Authors:Francisco Brevis Nuñez  Eva Tschiedel  Ursula Felderhoff-Mueser  Ulrich Neudorf  René Chapot  Christian Dohna-Schwake
Affiliation:1. Department of Neonatal and Pediatric Intensive Care Unit, Klinikum Duisburg, Zu den Rehwiesen 9, 47055, Duisburg, Germany
2. Division of Pediatric Critical Care, University Hospital of Essen, Essen, Germany
3. Pediatric Cardiology, University Hospital of Essen, Essen, Germany
4. Department of Neuroradiology, Alfried Krupp Hospital Essen, Essen, Germany
Abstract:

Introduction

This study reports the first cases of neurogenic stunned myocardium in two children with vein of Galen aneurysmal malformation after interventional treatment.

Patients

Two newborns with vein of Galen aneurysmal malformation and high output cardiac failure developed a severe reversible left ventricular dysfunction shortly after embolization, concurrently with acute hydrocephalus.

Results

There was a resolution of the cardiac symptoms of left ventricular dysfunction within a few days under treatment with milrinone and dobutamine.

Conclusions

Reversible left ventricular dysfunction is observed in adult patients mainly after subarachnoid hemorrhage and is called neurogenic stunned myocardium (NSM). Other forms of brain injuries have also been identified accounting for this condition in adults. In pediatric population especially with specific cerebral diseases, NSM may be underdiagnosed.
Keywords:
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