A randomized controlled trial of laparoscopic Nissen fundoplication versus proton pump inhibitors for the treatment of patients with chronic gastroesophageal reflux disease (GERD): 3-year outcomes期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

A randomized controlled trial of laparoscopic Nissen fundoplication versus proton pump inhibitors for the treatment of patients with chronic gastroesophageal reflux disease (GERD): 3-year outcomes

Authors:	Mehran Anvari Christopher Allen John Marshall David Armstrong Ron Goeree Wendy Ungar Charles Goldsmith

Affiliation:	(1) Department of Surgery, St. Joseph’s Healthcare, McMaster University, 50 Charlton Ave East, Hamilton, ON, L8N 4A6, Canada;(2) Firestone Institute of Respiratory Health, McMaster University, Hamilton, ON, Canada;(3) Department of Medicine, McMaster University, Hamilton, ON, Canada;(4) Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada;(5) Institute for Clinical Evaluative Sciences, Hospital for Sick Children, Toronto, ON, Canada

Abstract:	Background A randomized controlled trial (RCT) investigated patients with gastroesophageal reflux disease (GERD) who were stable and symptomatically controlled with long-term medical therapy to compare ongoing optimized medical therapy with laparoscopic Nissen fundoplication (LNF).

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