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Lymphatic transport from normal and synovitic knees in rabbits |
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| Authors: | Inge Reimann Dimitrios Vittas Steen Levin Nielsen Eiliv Svalastoga |
| Institution: | a Department of Orthopedics, University of Copenhagen, Herlev Hospital, Frederiksberg, Denmark b Department of Nuclear medicine, University of Copenhagen, Herlev Hospital, Frederiksberg, Denmark c Department of Small Animal Diseases and Clinical Practice, The Royal Veterinary and Agricultural University, Frederiksberg, Denmark |
| Abstract: | The resorption pattern of synovial fluid through the lymphatic system from normal and synovitic knee joints in rabbits was studied with 99mHechnetium-rhenium-sulfur colloid injected intraarticularly and monitored for 14 hours with a gamma camera.
On the normal side the regional lymph nodes were visualized after I hour and after 14 hours still 75 percent activity remained in the knee. In the synovitic knees no lymphatic transport could be detected; and the radiotracer was unstable with rapid liberation of technetium, which was excreted in the urine. This radiolysis was not found in vitro in synovitic joint fluid. The lymphatic transport from normal rabbit knees is low. We found a clear difference in lymphatic transport between normal and synovitic knee joints. |
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