Novel clonal der(8)t(8;14)(p11;q11),del(9)(q13q22) and t(14;22) (q13;q13) in a patient with fulminant adult T-cell leukemia/lymphoma |
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| Authors: | Yeh Su-Peng Yu Ming-Tsong Chow Kuan-Chih Lai Ling-Ya Chiu Chang-Fang |
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| Institution: | Division of Hematology and Oncology, Department of Internal Medicine, China Medical College Hospital, 2 Yuh Der Road, Taichung 404, Taiwan. superyeh@pavo.seed.net.tw |
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| Abstract: | We describe a 70-year-old man with fulminant adult T-cell leukemia/lymphoma. He died of progressive disease 1 week after the onset of symptoms. The integrated viral DNA of human T-lymphotropic virus type I was detected in the bone marrow aspirate by polymerase chain reaction. Cytogenetic analysis of bone marrow cells showed novel clonal aberrations consisting of 46,XY,der(8)t(8;14)(p11;q11),del(9) (q13q22),t(14;22)(q13;q13). |
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