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利培酮与奋乃静治疗老年精神分裂症对照研究
引用本文:范建华.利培酮与奋乃静治疗老年精神分裂症对照研究[J].临床精神医学杂志,2007,17(6):413-414.
作者姓名:范建华
作者单位:江苏南通市第四人民医院,226005
摘    要:目的:比较利培酮和奋乃静治疗老年精神分裂症的临床疗效和安全性。方法:对66例老年精神分裂症患者随机分为两组,分别服用利培酮和奋乃静。疗程8周。采用阳性与阴性症状量表(PANSS)评定疗效,用治疗中出现的症状量表(TESS)评定不良反应。结果:利培酮和奋乃静疗效相当。利培酮对阴性症状起效更快。结论:利培酮和奋乃静治疗老年精神分裂症疗效相仿,利培酮不良反应少而轻。

关 键 词:利培酮  奋乃静  老年  精神分裂症
文章编号:1005-3220(2007)06-0413-02
收稿时间:2006-12-11
修稿时间:2006-12-28

Comparative study of risperidone and perphenazine in senile schizophrenia
FAN Jian-hua.Comparative study of risperidone and perphenazine in senile schizophrenia[J].Journal of Clinical Psychological Medicine,2007,17(6):413-414.
Authors:FAN Jian-hua
Abstract:Objective:To compare the clinical effect and safety in senile schizophrenic patients treated by risperidone or perphenazine.Method:Sixty-six senile schizophrenic patients were randomly divided into risperidone group and perphenazine group,and then received treatments for 8 weeks.Positive and negative symptoms scale(PANSS)and treatment emergent symptom scale(TESS)were used to evaluate the efficacy and side effects respectively.Results:The effects were similar between risperidone and perphenzine,but the negative symptoms improved more quickly in risperidone group than in perphenzine group.Conclusion:Risperidone has similar effect to perphenazine in the treatment of senile schizophrenic patients,with fewer and lighter side effect
Keywords:risperidone  perphenazine  senile  schizophrenia
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