地胆草的化学成分和药理作用研究进展

地胆草 Elephantopus scaber Linn.为菊科地胆草属植物，产于美洲、亚洲、非洲等地区及我国的南方诸省，具有清热解毒、消肿利尿之功效，用于治疗感冒、胃肠炎、扁桃体炎、咽喉炎、结膜炎、肾炎水肿、疖肿等。地胆草含有倍半萜、三萜、黄酮等成分，近年来从中发现的倍半萜内酯类成分因具有强大抗肿瘤活性而备受关注。为了更好的发掘、利用地胆草资源，该文综述了其化学成分和药理作用研究进展。

Research Progress on Chemical Constituents of Elephantopus Scaber Linn. and Their Pharmacological Effects

Elephantopus scaber Linn. belongs to Elephantopus plant of Compositae, is originated in America, Asian, Africa area and the southern provinces of China, possesses the effects of clearing away heat and detoxification, detumescence and diuresis, and is used for treating cold, gastroenteritis, amygdalitis, sphagitis, conjunctivitis, nephritis edema and furuncle;Elephantopus scaber Linn. has the chemical constituents of sesquiterpenoids, triterpennoids and flavonoids;recently years, much attention were paid to Elephantopus scaber Linn. due to its potent anti-tumor activity of sesquiterpenoids isolated from Elephantopus scaber Linn. The research progress in the chemical con-stituents of Elephantopus scaber Linn. and their pharmacological effects is reviewed for better explore and utilize the Elephantopus scaber Linn. resource.