参归仁和剂联合心理干预治疗产后抑郁60例

目的 观察参归仁合剂联合心理干预治疗产后抑郁的临床疗效。方法 将120例产后抑郁患者随机分为治疗组和对照组,各60例。两组患者均给予综合性心理干预治疗,治疗组加用参归仁合剂治疗,以6周为1个疗程。于用药第3,6周末对两组患者进行爱丁堡产后抑郁量表（EPDS）评分、中医证候计分以评估疗效,并于产后第2,4,6周末进行焦虑自评量表（SAS）和抑郁自评量表（SDS）测定。结果 治疗第3,6周末,治疗组患者的EPDS评分和中医证候评分均明显低于对照组（P〈0.05）;治疗组患者的总有效率为93.33%,显著高于对照组的63.33%（P〈0.05）;治疗组患者在产后第4,6周末的SAS和SDS评分下降程度明显优于对照组（P〈0.05）。结论 参归仁和剂联合综合心理干预能有效改善产后抑郁症患者的抑郁情绪,安全有效,值得临床推广。

Clinical Efficacy of Shenguiren Mixture Combined with Psychological Intervention in Treating Postpartum Depression in 60 Cases

Objective To observe the clinical effect of Shenguiren Mixture combined with the psychological intervention in treating postpartum depression. Methods 120 patients with postpartum depression were randomly divided into the treatment group and control group,60 cases in each group. The two groups were given the comprehensive psychological intervention therapy, but the treatment group was added with Shenguiren Mixture with 6 weeks as one treatment course. The Edinburgh postnatal depression scale （EPDS） scores and the TCM syndrome scores at the end of 3,6 weeks were adopted to evaluate the curative effect. The self-rating anxiety scale （SAS） and self-rating depression scale（SDS） were detected at the end of 2,4,6 weeks in the two groups. Results The EPDS score and TCM syndrome score at the end of 3,6 weeks in the treatment group were significantly lower than those in the control group（P 〈 0.01）.The total effect rate of the treatment group and the control group were 93.33% and 63.33% respectively,the treatment group was significantly higher than the control group with statistical difference between the two groups（P 〈 0. 05）.The decrease degree of SAS and SDS scores at the end of 4,6 weeks in treatment group were significantly superior to that in the control group with statistical difference（ P 〈 0. 05）. Conclusion Shenguiren Mixture combined with the psychological intervention can effectively improve the depressive emotion of postpartum depression,which is safe and effective and worthy of clinical promotion.