Lack of SARS transmission and U.S. SARS case-patient |
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Authors: | Peck Angela J Newbern E Claire Feikin Daniel R Issakbaeva Elmira T Park Benjamin J Fehr Jason LaMonte Ashley C Le Thong P Burger Terry L Rhodes Luther V Weltman Andre Erdman Dean Ksiazek Thomas G Lingappa Jairam R;SARS Pennsylvania Case Investigation Team |
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Institution: | National Center for Infectious Diseases, Division of Viral and Rickettsial Diseases, Respiratory and Enteric Virus Branch, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. apeck@cdc.gov |
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Abstract: | In early April 2003, severe acute respiratory syndrome (SARS) was diagnosed in a Pennsylvania resident after his exposure to persons with SARS in Toronto, Canada. To identify contacts of the case-patient and evaluate the risk for SARS transmission, a detailed epidemiologic investigation was performed. On the basis of this investigation, 26 persons (17 healthcare workers, 4 household contacts, and 5 others) were identified as having had close contact with this case-patient before infection-control practices were implemented. Laboratory evaluation of clinical specimens showed no evidence of transmission of SARS-associated coronavirus (SARS-CoV) infection to any close contact of this patient. This investigation documents that, under certain circumstances, SARS-CoV is not readily transmitted to close contacts, despite ample unprotected exposures. Improving the understanding of risk factors for transmission will help focus public health control measures. |
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Keywords: | severe acute respiratory distress syndrome healthcare workers nosocomial transmission |
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