基层医院肺炎克雷伯菌的耐药现状调查

目的调查基层医院肺炎克雷伯菌的耐药现状,为临床医师合理用药提供依据.方法用K-B法做体外药敏试验,用纸片确证试验检测产超广谱β-内酰胺酶(ESBLs)细菌.结果我院肺炎克雷伯菌产ESBLs率为24.8%;137株肺炎克雷伯菌对亚胺培南100%敏感,对阿米卡星和环丙沙星耐药率约为40%,对其余6种常用抗生素耐药率均＞50%.结论基层医院也要重视细菌的耐药监测工作,预防医院感染的发生与流行.

Drug Resistance Status of Klebsiella pneumoniae in Montane Hospital

OBJECTIVE To investigate drug resistance status of Klebsiella offer scientific basis for reasonable usage of antibiotics. METHODS Drug pneurnoniae in montane hospital and resistance was analyzed by using K-B method. The ESBLs producing strains detected by disc confirmed test. RESULTS The frequency of ESBLs- producing K. pneumoniae isolates were 24. 8% in our hospital. All of the 137 strains were susceptible to imipenem. And the resistant rate to ciprofloxacin was 40%, the resistant rate to other 6 antibiotics was all above 50%. CONCLUSIONS Supervising drug resistance of clinical isolates in montane hospital is also important for prevention of nosocomial infection breaking out and surveillance.