艾灸对大鼠的胃粘膜保护作用及与血清铜锌含量的关系

本实验观察到艾灸＋溃疡组大鼠溃疡面积显著小于溃疡组（P＜0．05）;溃疡组血清铜／锌比值较对照组显著增高（P＜0．01）;艾灸＋溃疡组血清铜／锌比值较溃疡组显著降低（P＜0．01）。提示：艾灸对胃粘膜具有保护作用;胃溃疡时机体出现微量元素的代谢紊乱,而艾灸可改善机体的微量元素代谢,这很可能是艾灸对胃粘膜保护作用的机理之一。

The Effect of Moxibustion on Gastric Mucosa in Rats and Its Relation to Copper,Zinc Contents in Serum

18 rats were randomly deivided into 3 groups: control grup . the group merely with experimental gastric ulcer and the group with experimental gastric ulcer after 3-week moxibustion. The results showed: (1 ) moxibustion could significatly reduce the ulcer area of the rats (P<0. 05); (2 ) compared with control group, the experimental gastric ulcer model rats had an increase in copper content and Cu/Zu ratio, the differences were statistically significant (P<0. 05, P< 0. 01 ); (3 ) in contrast to the rats merely with experimental gastric ulcer, moxibustion-pretreated rats had a significant increase in Zinc content in serum (P<0, 01 ), but its copper content and Cu/Zn ratio in serurn were significantly decreased (P< 0. 05, P< 0. 01 ). The results confirmed that moxibustion pretreatment at "Shen Jue'could protect the gastric mucosa from strass-induced uleer, having protective effect on gastric mucosa. The results also suggested that there was a disbalance .in trace elements metabolism, but moxibustion could improve it. This was most likely to be one of the mechanisms of moxibustion protection on gastrip mucosa