中医血瘀证与类风湿性关节炎的关系研究(针刺活血化瘀效应观察)

本文通过对31例类风湿性关节炎（下简称RA）患者的临床观察和假性RA大鼠模型的实验研究，并运用整体和局部治疗相结合的针刺方法，发现：绝大部分RA患者有血瘀体征和血液流变学异常，有统计学差异；模型组大鼠四肢关节、耳朵、尾巴发生红肿，近端趾间关节有梭形趾发生，血液流变学异常和血小板聚集率增高，有统计学差异。针刺后，RA患者和模型组大鼠的以上指标，均得到明显改善，有统计学差异。提示（1）RA与血瘀证之间关系非常密切；（2）针刺具有活血化瘀作用；（3）血液流变学检查可作为RA活动程度及疗效评定标准之一。

A Study of Relation Between Rheumatoid Arthritis(RA) and Blood Stasis──the effect of acupuncture promoting blood circulation to remove blood stasis

In this article, the clinical 31 cases patients with Rheumatoid artritis (RA) were observed and animal experiments were carried out on RA model rats and the treatrnent of acupuncture with combination of the different points was adopted. It was found that most of the 31 cases of RA patients had the signs of bloods stasis and abnormal hemorheology, statistical analysis indicated that there were significant differents between RA patients and healthy person- Red and swelling in joints of four limbs, ear and tail, clubbed toes,abnormal hemorheology, high in blood platelet aggregation and so on were found in model rats of RA, statistically, sinificant differents also exist between model rats of RA and healthy rats. The above indesexes in patients and model rats of RA were significantly improved after acupuncture treatment, which suggested that (1) there be a close relation between RA and blood stasis. (2) acupuncture play a role of promoting blood circulation to rernove blood stasis.(3) examination of hemorheology may be one of standards that development of RA and curative effect