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Lithium-induced nephrotic syndrome in a young pediatric patient
Authors:Abdullah Sakarcan  David B. Thomas  Kevin P. O’Reilly  Robert W. Richards
Affiliation:(1) Department of Pediatrics, University of South Carolina School of Medicine, Columbia, South Carolina, USA, US;(2) 8 Medical Park, Department of Pediatrics, Division of Pediatric Nephrology, Columbia, SC 29203, USA e-mail: abdullahsakarcan@hotmail.com Tel.: +1-803-4342394, Fax: +1-803-4343855, US;(3) Department of Pathology and Laboratory Medicine, University of North Carolina Hospitals, North Carolina, USA, US;(4) Division of Nephrology and Hypertension, University of North Carolina Hospitals, North Carolina, USA, US;(5) Greenville Psychiatry, Greenville, South Carolina, USA, US
Abstract:Lithium-induced nephrotic syndrome is a rare complication of lithium therapy and is even rarer in children. Most reported cases have been secondary to minimal change disease, which reverses within 1–4 weeks on discontinuation of lithium therapy. However, focal glomerulosclerosis (FSGS) has occasionally been reported and is not always reversible with discontinuation of lithium. We report an 11-year-old child with lithium-induced FSGS nephrotic syndrome who went into full remission after lithium was discontinued. Received: 11 June 2001 / Revised: 9 October 2001 / Accepted: 9 October 2001
Keywords:  Lithium  Focal segmental glomerulosclerosis  Nephrotic syndrome
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