非小细胞肺癌术后辅助化疗和靶向治疗的临床疗效对比分析

目的 比较观察术后辅助化疗和易瑞沙用于Ⅲa期非小细胞肺癌(NSCLC)的术后辅助治疗的疗效.方法 入组76例Ⅲa期行完全性切除术的NSCLC,选择口服易瑞沙治疗33例,选择术后辅助化疗43例.治疗结束后分别观察两组的生存情况.结果 易瑞沙组1、2年生存率分别为93.9%和51.5%,化疗组分别为88.4%和48.8%,...

The Comparative Analyses of Curative Effect of Postoperative Adjuvant Chemotherapy and Targeted Therapy in the Treatment of Non Small Cell Lung Cancer

Objective To analyze the curative effect of postoperative adjuvant chemotherapy and iressa in the treatment of stage Ⅲa non small cell lung cancer(NSCLC) after operation.Methods All the 76 patients with stage Ⅲa NSCLC received complete resection,and the 33 patients taked iressa,the other 43 patients received postoperative adjuvant chemotherapy.After treatment,the survival rates and the median disease-free survival time of the two groups were observed respectively.Results The 1-and 2-year rates were 93.9% and 51.5% in the iressa group,and were 88.4% and 48.8% in the chemotherapy group(P>0.05).The median disease-free survival time was 13 months in the iressa group,and was 12 months in the chemotherapy group(P>0.05).Conclusion The survival rates and the median disease-free survival time of the patients with stage Ⅲa NSCLC who take iressa are similar to those of the patients who receive postoperative adjuvant chemotherapy.