湿房镜对翼状胬肉切除术后眼表的影响

目的:探讨湿房镜对翼状胬肉术后眼表环境的影响。方法:收集复旦大学附属中山医院厦门医院眼科就诊的40例翼状胬肉患者(40只眼)病例资料,随机分为湿房镜组和对照组,每组20只眼。所有患者均采用翼状胬肉切除联合自体结膜移植术,术后均给予妥布霉素地塞米松滴眼液和0.3%玻璃酸钠滴眼液治疗。湿房镜组患者术后第2天开始佩戴湿房镜,对照组患者无特殊处理。记录2组患者术前、术后1周、1个月、3个月的眼表疾病指数调查表(ocular surface disease index,OSDI),非侵入性泪河高度,非侵入性泪膜破裂时间(non-invasive tear break-up time, NIKBUT),眼红分析(包括鼻侧球结膜充血、鼻侧睫状充血、球结膜充血等参数),采用重复测量资料方差分析进行比较。结果:不同时间各类眼表指标差异有统计学意义(组内时间效应P0.05),湿房镜组和对照组OSDI评分、NIKBUT、鼻侧球结膜充血、鼻侧睫状充血和球结膜充血状况差异有统计学意义(P0.05)。结论:湿房镜能够加速翼状胬肉术后眼表的修复,减少患者术后不适。

Effect of moisture chamber spectacles on ocular surface after pterygium excision

Objective: To explore the effect of moisture chamber spectacles on ocular surface after pterygium excision by Oculus Keratograph. Methods: A total of 40 patients (40 eyes) with pterygium were recruited and randomly divided into two groups:moisture chamber spectacles group and control group (20 eyes in each group). All cases received pterygium excision and conjunctival autograft transplantation, and tobramycin dexamethasone eye drops and 0.3% sodium hyaluronate after surgery. Patients in moisture chamber spectacles group wear moisture chamber spectacles the day after surgery. Ocular surface disease index (OSDI), noninvasive Keratograph tear meniscus height (NIKTMH), noninvasive Keratograph tear breakup time (NIKBUT), eye red analyses (nasal conjunctival hyperemia index, nasal ciliary hyperemia index, and conjunctival hyperemia index) before operations and at 1 week, 1 and 3 months after operations were recorded and analyzed using analysis of variance based on repeated measurement data. Results: Time had a significant effect on those ocular surface index (tests of between-subjects effects P<0.05). The differences of OSDI, NIKBUT, nasal conjunctival hyperemia index, nasal ciliary hyperemia index, and conjunctival hyperemia index between two groups were statistically significant (tests of between-subjects effects P<0.05); time had a significant effect on those ocular surface index (tests of between-subjects effects P<0.05). Conclusions: Wearing moisture chamber spectacles can significantly speed the repair of the ocular surface and reduce postoperative discomfort in pterygium patients.