经黏膜下隧道憩室间脊切开术治疗食管憩室患者的生存质量分析

目的:探讨经黏膜下隧道憩室间脊切开术(submucosal tunneling endoscopic septum division, STESD)对食管憩室患者生存质量的改善情况。方法:回顾性分析2016年4月至2018年4月在复旦大学附属中山医院接受STESD治疗的11例食管憩室患者的临床资料,包括术前术后的食管造影和内镜检查资料、术前及术后5个月SF-36量表评分。结果:出现黏膜损伤2例,无严重并发症。3例(27.3%)在最后一次随访时症状消失,7例(63.6%)症状得到缓解。术前、术后SF-36量表总分分别为(116.0±23.6)分和(135.1±9.0)分(P=0.014)。所有患者术后的一般健康状况、精力和精神健康状况均较术前均有显著改善(P=0.003,P=0.006,P=0.037)。结论:STESD是一种安全有效的内镜微创手术,能有效提高食管憩室患者的生存质量。

Quality of life changes after submucosal tunneling endoscopic septum division for esophageal diverticulum

Objective: To explore the improvement of quality of life of patients with esophageal diverticulum by submucosal tunneling endoscopic septum division (STESD).Methods: Clinical data of 11 patients who had received STESD for esophageal diverticulum from April 2016 to April 2018 were retrospectively analyzed. Esophagograms and endoscopic examination were assessed before and after the operation. All patients completed the assessment of the SF-36 scale before STESD and 5-month after the surgery.Results: Mucosal injury occurred in 2 patients. No severe complications were observed. Three patients (27.3%) were completely symptom-free till the last follow-up, and 7 (63.6%) reported relieved symptoms. The total scores of SF-36 scale before and after the procedure were (116.0±23.6) and (135.1±9.0) points respectively (P=0.014). General health, vitality and mental health after surgery showed significant improvement than those before surgery (P=0.003, P=0.006, and P=0.037, respectively).Conclusions: STESD is a safe and valid endoscopic minimal invasive surgery, and it can efficiently improve patients'' quality of life.