乳腺肿瘤常规超声联合超声造影影像组学特征与乳腺癌分子分型相关性的研究进展

影像组学（radiomics）是一种从医学影像中高通量地提取影像特征来深入挖掘内部数据信息的技术方法，通过肿瘤分割、特征提取与模型建立来辅助临床对肿瘤的诊断与治疗。在精准医疗时代，乳腺癌（breast cancer，BC）的个体化早期诊治尤为重要。常规超声是诊断乳腺肿瘤的重要影像学方法，超声造影（contrast enhanced ultrasound，CEUS）可以实时显示乳腺肿瘤微血管灌注的形态学及功能学变化，在此基础上产生的超声及超声造影影像组学在乳腺肿瘤良恶性诊断及判断乳腺癌分子分型中具有潜在临床应用价值。本文就乳腺肿瘤常规超声联合超声造影影像组学特征与乳腺癌分子分型相关性方面进行综述。

Research progress of the correlation between conventional ultrasound combined with contrast-enhanced ultrasound radiomics features of breast tumors and molecular types of breast cancer

Radiomics is a technique method of utilizing the high-throughput extraction of features from medical images to achieve tumor segmentation, feature extraction and model foundation. It could assist the clinical diagnosis and treatment of tumors by mining, analyzing and predicting a large amount of deep data information. In the era of precision medicine, the early individual diagnosis and treatment of breast cancer (BC) are especially important.Conventional ultrasound is an important imaging method for the diagnosis of breast tumors.Contrast-enhanced ultrasound (CEUS) can reflect the morphological and functional changes of microvascular perfusion of breast tumors in real time. On the basis of conventional ultrasound and CEUS, the radiomics has potential of clinical application in the differential diagnosis of benign and malignant breast tumors and molecular classification of breast cancer. This paper reviews the correlation between conventional ultrasound combined with CEUS radiomics features of breast tumors and breast cancer molecular typing of breast cancer.