实时三维超声VPQ技术定量评价颈动脉斑块的临床应用价值

目的 应用实时三维超声VPQ检测技术与CTA血管成像技术分别测定颈动脉斑块所致血管狭窄程度，评价三维超声VPQ技术定量评价颈动脉斑块的临床应用价值。 方法 对102例患者的颈动脉分别进行实时三维超声及CTA检查，评估共130个颈动脉斑块所致局部血管狭窄的程度。应用实时三维超声VPQ技术脱机分析测定面积狭窄率、内中膜厚度、最窄处斑块厚度、NWI（标化壁指数）及斑块回声强度等数值。同期应用CTA测定颈动脉狭窄程度，并与三维超声VPQ技术测得的狭窄程度对比。 结果 实时三维超声与CTA判定颈动脉狭窄程度相比较，诊断准确性高，可很好显示颈动脉斑块的位置、管壁结构并测得相关参数。实时三维超声测得颈动脉局部管腔轻度狭窄15处、中度狭窄78处，重度狭窄37处；CTA测得颈动脉局部管腔轻度狭窄11处，中度狭窄71处，重度狭窄48处。实时三维超声与CTA对颈动脉斑块所致管腔狭窄程度的检测具有高度一致性，具有统计学意义（P<0.01），实时三维超声VPQ技术测得颈动脉不同狭窄程度的NWI值比较差异有统计学意义（P<0.05）。 结论 实时三维超声VPQ技术能够准确测定颈动脉斑块所致血管狭窄程度，操作简便易行，可获得较二维超声更详细的参数，并对相关指标可进行量化分析，具有重要的临床应用价值。

Clinical Value of Real-time Three-dimensional Ultrasound VPQ Technology in Quantitative Evaluation of Carotid Plaque

Objective To explore the clinical value of real-time three-dimensional ultrasound (RT-3DU) VPQ technology diagnosis of carotid stenosis. Methods 102 patients of carotid plaque were examined with RT-3DU and CTA. The degree of stenosis with respect to the 130 locations of carotid plaque was evaluated. RT-3DU VPQ technology for off-line analysis was applied, such as carotid stenosis, the thickness of intima-media, the thickness of the narrowest plaque, NWI (normalized wall index) and the echo intensity of plaque. During the same period, the degree of carotid stenosis was detected CTA, the two methods was compared with each other. Results There was high consistency between RT-3DU and CTA. The locations of carotid plaque and the structure of carotid wall can be shown. RT-3DU showed mild stenosis in 15 cases, moderate stenosis in 78 cases and severe stenosis in 37 cases. CTA showed mild stenosis in 11 cases, moderate stenosis in 71 cases and severe stenosis in 48 cases. RT-3DU and CTA detection of carotid stenosis had a high consistency, and showed statistically significant (P<0.01). Conclusions RT-3DU VPQ technology could be determined carotid stenosis, easy and simple to handle, and capable of quantitative analysis of related indexes, while provided specific parameters, and its clinical application was very important.