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| HPLC法测定复方感冒灵片中对乙酰氨基酚和咖啡因的含量 | |
| 引用本文： | 张翠玲,宋菲,李华玉. HPLC法测定复方感冒灵片中对乙酰氨基酚和咖啡因的含量[J]. 齐鲁药事, 2004, 23(5): 28-29 |
| 作者姓名： | 张翠玲 宋菲 李华玉 |
| 作者单位： | 1. 泰安荣军医院,泰安,275000 2. 蒙阴县中医院,蒙阴,276200 3. 临沂市药品检验所,临沂,276000 |
| 摘 要： | 目的 用HPLC法测定复方感冒灵片中对乙酰氨基酚和咖啡因含量。方法 RP-HPLC法。结果 对乙酰氨基酚在20～60μg·ml-1,咖啡因在2～6μg·ml-1浓度范围呈良好线性关系,平均回收率分别为99.09%(RSD =1.60%)、101.4%(RSD =1.85%)。结论 用HPLC法测定复方感冒灵片中对乙酰氨基酚和咖啡因含量方法准确、灵敏度高、重现性好。 |
| 关 键 词： | HPLC 对乙酰氨基酚 咖啡因 含量 |
| 文章编号： | 1672-7738(2004)05-0028-02 |
Determination of Acetaminophen and Caffeine in Compound Ganmaoling Tablets by HPLC |
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| Zhang Cui-ling,Song Fei,Li Hua-yu. Determination of Acetaminophen and Caffeine in Compound Ganmaoling Tablets by HPLC[J]. qilu pharmaceutical affairs, 2004, 23(5): 28-29 | |
| Authors: | Zhang Cui-ling Song Fei Li Hua-yu |
| Affiliation: | Zhang Cui-ling,Song Fei1,Li Hua-yu2 |
| Abstract: | Objective To establish a method for determination of Acetaminophen and Caffeine in Compound GanmaolingTablets by HPLC. Methods Used the method of RP-HPLC. Results A linearity was obtained from 20 to 60 μg·ml-1 of Acetami-nophen (r =0.9998) and from 2 to 6μg·ml-1 of Caffeine (r =0.9997). The average recoveries were 99.09% (RSD =1.60%)and 101.4%(RSD =1.85%). Conclusion The method of HPLC was accurate and sensitive for the determination of Acetaminophen and Caffeineof compound Ganmaoling Tablets with high recovery. |
| Keywords: | HPLC Acetaminophen Caffeine content |
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