超声热疗技术的发展与应用

超声热疗很早就被用于治疗癌症及良性肿瘤，生物学实验和临床表明：41℃-45℃的热疗能显著增强放疗和化疗的疗效，而高于65℃的高温热疗可以代替传统的介入式疗法来摧毁肿瘤组织，使肿瘤组织凝固、坏死、脱落。高强度降焦超声（HIFU）能在短时间内使癌变组织的温度升至65℃以上，导致病变组织凝固、坏死，高强度聚集超声作为一种具有巨大潜力的、无损的、有效的局部治疗手段，受到普遍关注。目前，中国在高强度聚焦超声临床上已处于世界领先水平。文中介绍了超声热疗技术的发展和应用。

Development and Application of Ultrasound Technology for Hyperthermia

It has been a long time since ultrasound hyperthermia began to be used in the clinical management of cancers and benign diseases. Numerous biological and clinical investigations have demonstrated that: hyperthermia in the range of 41-45 degrees C can significantly enhance clinical response to radiation therapy and chemotherapy, and high-temperature hyperthermia (greater than 65 degrees C) alone is now being used as an alternative to conventional invasive surgery for selective tissue destruction, causing tumor coagulation and necrosis. As a promising noninvasive and effective local therapy, HIFU has attracted great attention. China is advanced in the clinical applications of HIFU. This article gives an introduction of the development and applications of ultrasound hyperthermia technology, and also provides a general review of a selection of ultrasound hyperthermia systems both in clinical use and under development.